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Recombinant Human Complexin-1 His Protein

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SDS-Page: Recombinant Human Complexin-1 Protein [NBC1-18349] - Complexin 1, 17.1 kDa (154 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

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Recombinant Human Complexin-1 His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-134 of Human Complexin-1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE AVRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEVE EEDESILDTV IKYLPGPLQD MLKK

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CPLX1
Purity
>90%, by SDS-PAGE
Endotoxin Note
< 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
17.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human Complexin-1 His Protein

  • complexin 1
  • Complexin I
  • Complexin-1
  • CPLX1
  • CPX I
  • CPX1
  • CPX-I
  • synaphin 2
  • Synaphin-2

Background

Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for Complexin-1 Recombinant Protein (NBC1-18349) (0)

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FAQs for Complexin-1 Recombinant Protein (NBC1-18349). (Showing 1 - 1 of 1 FAQ).

  1. We purchased this protein from you guys and I need its sequence.
    • NBC1-18349: full length protein, aa 1-134, with his-tag.

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Bioinformatics

Gene Symbol CPLX1