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Claudin-18.2 Antibody (zolbetuximab) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
zolbetuximab
Clonality
Monoclonal
Host
Human
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28796AF350
Alexa Fluor 405
NBP3-28796AF405
Alexa Fluor 488
NBP3-28796AF488
Alexa Fluor 532
NBP3-28796AF532
Alexa Fluor 594
NBP3-28796AF594
Alexa Fluor 647
NBP3-28796AF647
Alexa Fluor 700
NBP3-28796AF700
Alexa Fluor 750
NBP3-28796AF750
Allophycocyanin
NBP3-28796APC
Biotin
NBP3-28796B
DyLight 350
NBP3-28796UV
DyLight 405
NBP3-28796V
DyLight 488
NBP3-28796G
DyLight 550
NBP3-28796R
DyLight 594
NBP3-28796DL594
DyLight 650
NBP3-28796C
DyLight 680
NBP3-28796FR
DyLight 755
NBP3-28796IR
FITC
NBP3-28796F
HRP
NBP3-28796H
Janelia Fluor 525
NBP3-28796JF525
Janelia Fluor 549
NBP3-28796JF549
Janelia Fluor 646
NBP3-28796JF646
Janelia Fluor 669
NBP3-28796JF669
PE
NBP3-28796PE
PerCP
NBP3-28796PCP
Unconjugated
NBP3-28796-100ug
mFluor Violet 450 SE
NBP3-28796MFV450
mFluor Violet 500 SE
NBP3-28796MFV500
mFluor Violet 610 SE
NBP3-28796MFV610
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Claudin-18.2 Antibody (zolbetuximab) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
CLDN18.2
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
CLDN18
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Claudin-18.2 Antibody (zolbetuximab) [CoraFluor™ 1]

  • claudin-18
  • SFTA5
  • SFTPJ
  • surfactant associated 5
  • surfactant associated protein J
  • surfactant, pulmonary associated protein J

Background

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Claudin-18.2
Antibody (zolbetuxima ...
NBP3-28796CL1
Claudin-18.2 Antibody (zolbetuximab) [CoraFluor™ 1]
Species: Hu
Applications: ELISA, Flow, Func

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Bioinformatics

Gene Symbol CLDN18