Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/414) [NBP2-29428] - Formalin-fixed, paraffin-embedded pancreas stained with Chromogranin A Ab (CGA414).
Immunohistochemistry-Paraffin: Chromogranin A Antibody (CGA/414) [NBP2-29428] - Formalin-fixed, paraffin-embedded human small cell Lung Carcinoma stained with Chromogranin A Monoclonal Antibody (CGA/414)
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-33198)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant full-length human Chromogranin A protein (Uniprot: P10645)
Localization
Finely granular cytoplasmic
Marker
Neuroendocrine Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CHGA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Publications
Read Publications using NBP2-29428 in the following applications:
Mouse reactivity reported in scientific literature (PMID: 29352046).
Packaging, Storage & Formulations
Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified
Alternate Names for Chromogranin A Antibody (CGA/414)
betagranin (N-terminal fragment of chromogranin A)
Betagranin
Catestatin
CGA
CHGA
Chromofungin
chromogranin A (parathyroid secretory protein 1)
Chromogranin A
chromogranin-A
Pancreastatin
Parastatin
Parathyroid Secretory Protein 1
Pituitary Secretory Protein I
SP-I
Background
Chromogranin A is found in secretory vesicles of neurons and endocrine cells. It is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Zhou J, Sheridan M, Tian Y et al. Development of Properly-Polarized Trophoblast Stem Cell-Derived Organoids to Model Early Human Pregnancy SSRN Electronic Journal 2022-11-02
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FAQs for Chromogranin A Antibody (NBP2-29428). (Showing 1 - 1 of 1 FAQs).
I have following question about antibodies against Chromogranin A. Your products list the species but canine is not included. Does it mean that the products cannot be used on canine tissues?
When we do not list a species, it means we have not tested an antibody to work with those samples. If we test an antibody and find that it does not work, we will list the species with a minus sign. Unfortunately, we haven't tried these abs on canine tissues and they may work, but we cannot guarantee it. If you would like to purchase one to try, you will be eligible for the Innovators Reward Program.
Beta Tubulin III and neurogenesis Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr... Read full blog post.
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