CHAF1A Antibody (SS 1 1-13)

Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ICC/IF, IP, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NB500-207	Applications	Species
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins The in v ivo Interaction Landscape of Histones H3.1 and H3.3 Molecular & Cellular Proteomics : MCP 2022-09-09 [PMID: 36089195]
Cohen C, Corpet A, Maroui MA et al. Promyelocytic Leukemia (PML) Nuclear Bodies (NBs) Induce Latent/Quiescent HSV-1 Genomes Chromatinization Through a PML-NB/Histone H3.3/H3.3 Chaperone Axis. bioRxiv [PMID: 30235352] (ICC/IF, Human)	ICC/IF	Human
Rivera C, Saavedra F, Alvarez F et al. Methylation of histone H3 lysine 9 occurs during translation. Nucleic Acids Res. 2015-09-24 [PMID: 26405197] (WB, Human)	WB	Human
Galvani, A et al. In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells. Mol Cell Biol;28(11):3672-85. 2008-06-01 [PMID: 18378699]
Ghosh JC et al. Hsp60 regulation of tumor cell apoptosis. J Biol Chem;283(8):5188-94. 2008-02-22 [PMID: 18086682]
Mocquet V, Laine JP, Riedl T et al. Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step. EMBO J 2008-01-09 [PMID: 18079701] (Human)		Human
Naryzhny, S et al. Proliferating cell nuclear antigen (PCNA) may function as a double homotrimer complex in the mammalian cell. J Biol Chem;280(14):13888-94. 2005-04-08 [PMID: 15805117] (IP, Human)	IP	Human
Jiao, R et al. Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. Mol Cell Biol;24(11):4710-9. 2004-06-01 [PMID: 15143166]
Green, CM, Almouzni, G. Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo. EMBO J;22(19):5163-74. 2003-10-01 [PMID: 14517254] (ICC/IF, Human)	ICC/IF	Human
Shibahara, K, Stillman, B. Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell;96(4):575-85. 1999-02-19 [PMID: 10052459] (ICC/IF, IP, Human)	ICC/IF, IP	Human
Yun HYH Molecular Characterization of Oncogenic H3. 3 K27M and G34R Histone Mutants Thesis 2021-01-01
Show All 11 Publications. Collapse Publications.

Array NB500-207

• CHAF1A Antibodies
• CHAF1A Lysate