Reactivity | MuSpecies Glossary |
Applications | Flow |
Clone | 446703 |
Clonality | Monoclonal |
Host | Rat |
Conjugate | Alexa Fluor 594 |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
Immunogen | HEK293 human embryonic kidney cell line transfected with mouse CD63 Met1-Met238 Accession # P41731 |
Specificity | Detects mouse CD63 in direct ELISAs. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Rat |
Gene | CD63 |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
Storage | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Preservative | 0.09% Sodium Azide |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
CD63, also known as LAMP-3 or ME491 (melanoma-associated antigen), is a 30-60 kDa member of the tetraspanin superfamily of protein trafficking proteins. CD63 is ubiquitously expressed and found in late endocytic vesicles, but following cell activation is also present on the plasma membrane. Interaction of CD63 with other membrane proteins or adaptors regulates cell activities such as adhesion, migration and degranulation. Extracellular regions of mouse CD63 share 94% and 67% amino acid sequence identity with rat and human CD63, respectively.
Secondary Antibodies |
Isotype Controls |
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CD63: is it pro-metastatic or anti-metastatic? CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several cellular signaling cascades along with acting as TIMP1 receptor. It is expressed by activated platelets, monocytes,... Read full blog post. |
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