CD24 Antibody (SN3)

CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: FLOW.

Showing Publications 1 - 8 of 8.

Publications using NB100-64861	Applications	Species
Zhang, W;Zeng, Y;Xiao, Q;Wu, Y;Liu, J;Wang, H;Luo, Y;Zhan, J;Liao, N;Cai, Y; An in-situ peptide-antibody self-assembly to block CD47 and CD24 signaling enhances macrophage-mediated phagocytosis and anti-tumor immune responses Nature communications 2024-07-06 [PMID: 38971872]
Todoroki K, Abe Y, Matsuo K et Al. Prognostic effect of programmed cell death ligand 1/programmed cell death 1 expression in cancer stem cells of human oral squamous cell carcinoma Oncol Lett 2024-02-01 [PMID: 38249811]
Chou CW, Hung CN, Chiu CH et al. Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination Nature communications 2023-10-17 [PMID: 37848444] (FLOW, Human)	FLOW	Human
Aroldi A, Mauri M, Ramazzotti D et al. Effects of blocking CD24 and CD47 'don't eat me' signals in combination with rituximab in mantle-cell lymphoma and chronic lymphocytic leukaemia Journal of cellular and molecular medicine 2023-08-31 [PMID: 37654003] (FLOW, Human)	FLOW	Human
Zuo Q, Yang Y, Lyu Y, Yang C, Chen C, Salman S, Huang T, Wicks E, Jackson W, Datan E, Qin W, Semenza G Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis. Cell Rep, 2023-02-28;42(3):112164. 2023-02-28 [PMID: 36857181]
Chen K, Dai M, Luo Q et al. PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer The international journal of biochemistry & cell biology 2022-12-27 [PMID: 36584909]
Takashima K, Fujii S, Komatsuzaki R et al. CD24 and CK4 are upregulated by SIM2, and are predictive biomarkers for chemoradiotherapy and surgery in esophageal cancer Int J Oncol 2020-01-17 [PMID: 32124945]
Barkal AA, Brewer RE, Markovic M et al. CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy Nature 2019-08-01 [PMID: 31367043] (FLOW, Human)	FLOW	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	3 reviewed by: Verified Customer	Immunofluorescence - paraffin	Human	03/25/2020	View Summary Application Other Sample Tested Gastric carcinoma Species Human Lot N/A Comments Comments pH 9 antigen retrieval

Array NB100-64861

• CD24 Antibodies
• CD24 ELISA Kits
• CD24 Proteins
• CD24 Proteins and Enzymes