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CD1c/BDCA-1 Antibody (L161) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IP
Clone
L161
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

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CD1c/BDCA-1 Antibody (L161) [DyLight 405] Summary

Additional Information
Clone L161 was used by HLDA to establish CD designation.
Immunogen
human thymocytes
Specificity
The antibody MEM-97 reacts with CD20 (Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD1C
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow (Cell Surface)
  • Flow Cytometry
  • Immunohistochemistry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD1c/BDCA-1 Antibody (L161) [DyLight 405]

  • BDCA1
  • BDCA-1
  • c polypeptide
  • CD1
  • CD1A
  • CD1c antigen
  • CD1c molecule
  • CD1c
  • cortical thymocyte antigen CD1C
  • differentiation antigen CD1-alpha-3
  • R7
  • T-cell surface glycoprotein CD1c

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD1C