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CCL8/MCP-2 Antibody (CCL8/3686) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
CCL8/3686
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-14174AF350
Alexa Fluor 405
NBP3-14174AF405
Alexa Fluor 488
NBP3-14174AF488
Alexa Fluor 532
NBP3-14174AF532
Alexa Fluor 594
NBP3-14174AF594
Alexa Fluor 647
NBP3-14174AF647
Alexa Fluor 700
NBP3-14174AF700
Alexa Fluor 750
NBP3-14174AF750
Allophycocyanin
NBP3-14174APC
Biotin
NBP3-14174B
DyLight 350
NBP3-14174UV
DyLight 405
NBP3-14174V
DyLight 488
NBP3-14174G
DyLight 550
NBP3-14174R
DyLight 594
NBP3-14174DL594
DyLight 650
NBP3-14174C
DyLight 680
NBP3-14174FR
DyLight 755
NBP3-14174IR
FITC
NBP3-14174F
HRP
NBP3-14174H
Janelia Fluor 525
NBP3-14174JF525
Janelia Fluor 549
NBP3-14174JF549
Janelia Fluor 646
NBP3-14174JF646
Janelia Fluor 669
NBP3-14174JF669
PE
NBP3-14174PE
PerCP
NBP3-14174PCP
Unconjugated
NBP3-13771-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-13771-100ug
Azide and BSA Free
NBP3-14174
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CCL8/MCP-2 Antibody (CCL8/3686) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Human recombinant CCL8/MCP-2 protein fragment (around aa1-99) (exact sequence is proprietary) (Uniprot: P80075)
Localization
Secreted
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCL8
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CCL8/MCP-2 Antibody (CCL8/3686) [CoraFluor™ 1]

  • C-C motif chemokine 8
  • CCL8
  • chemokine (C-C motif) ligand 8
  • HC14
  • MCP2
  • MCP-2
  • member 8 (monocyte chemotactic protein 2)
  • monocyte chemoattractant protein 2
  • SCYA10
  • small-inducible cytokine A8

Background

MCP2 and MCP3 are two recently identified monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and MCP3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. MCP3 also shares 58% amino acid identity with MCP2. Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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(292 Publications)
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CCL8/MCP-2
Antibody (CCL8/3686) ...
NBP3-14174CL1
CCL8/MCP-2 Antibody (CCL8/3686) [CoraFluor™ 1]
Species: Hu
Applications: IHC

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Bioinformatics

Gene Symbol CCL8