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Recombinant Human CCL25/TECK Protein

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SDS-Page: Human CCL25/TECK Protein [NBP2-35039]
SDS-Page: Human CCL25/TECK Protein [NBP2-35039]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, Bioactivity
Format
Carrier-Free
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier-Free
NBP2-35039-1mg
Carrier-Free
NBP2-35039-100ug
Carrier-Free
NBP2-35039-500ug
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Recombinant Human CCL25/TECK Protein Summary

Description
A single, non-glycosylated polypeptide chain containing 128 amino acids corresponding to CCL25/TECK Source: E. coli

Uniprot ID: O15444

Amino Acid Sequence: MQGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL
Details of Functionality
TECK protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CCL25
Purity
> 97 % pure by SDS-PAGE and HPLC
Endotoxin Note
Less than 1 EU/ug of CCL25/TECK as determined by LAL method.

Applications/Dilutions

Dilutions
  • Bioactivity
  • SDS-Page
Theoretical MW
14.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Preservative
No Preservative
Concentration
LYOPH
Purity
> 97 % pure by SDS-PAGE and HPLC
Reconstitution Instructions
Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Human CCL25/TECK Protein

  • C-C motif chemokine 25
  • CCL25
  • chemokine (C-C motif) ligand 25
  • Chemokine TECK
  • Ck beta-15
  • Ckb15
  • SCYA25TECKvar
  • small inducible cytokine subfamily A (Cys-Cys), member 25
  • Small-inducible cytokine A25
  • TECK
  • TECK/CCL25
  • TECKMGC150327
  • thymus expressed chemokine
  • Thymus-expressed chemokine

Background

CCL25 is new member of CC family chemokine. It is also called Thymus-expressed chemokine (TECK) because it is restricted produced by thymus and intestine. Especially, the dendritic cells derived from thymus but not bone marrow had identified to be the source of CCL25. By binding with CCR9, it elicits its effects of chemotactic for thymocytes, macrophages, and dendritic cells. Additionally, CCL25 takes part in regulating the development of T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CCL25
Uniprot