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CCL2/MCP1 Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, GpSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-41209AF350
Alexa Fluor 405
NBP2-41209AF405
Alexa Fluor 488
NBP2-41209AF488
Alexa Fluor 532
NBP2-41209AF532
Alexa Fluor 594
NBP2-41209AF594
Alexa Fluor 647
NBP2-41209AF647
Alexa Fluor 700
NBP2-41209AF700
Alexa Fluor 750
NBP2-41209AF750
Biotin
NBP2-41209B
CoraFluor 1
NBP2-41209CL1
DyLight 350
NBP2-41209UV
DyLight 405
NBP2-41209V
DyLight 550
NBP2-41209R
DyLight 594
NBP2-41209DL594
DyLight 650
NBP2-41209C
DyLight 680
NBP2-41209FR
DyLight 755
NBP2-41209IR
FITC
NBP2-41209F
HRP
NBP2-41209H
Janelia Fluor 525
NBP2-41209JF525
Janelia Fluor 549
NBP2-41209JF549
Janelia Fluor 646
NBP2-41209JF646
Janelia Fluor 669
NBP2-41209JF669
PerCP
NBP2-41209PCP
Unconjugated
NBP2-41209
mFluor Violet 450 SE
NBP2-41209MFV450
mFluor Violet 500 SE
NBP2-41209MFV500
mFluor Violet 610 SE
NBP2-41209MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-41209
BSA Free
NBP2-41209
BSA Free
NBP2-41209-0.025mg
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CCL2/MCP1 Antibody [DyLight 488] Summary

Immunogen
Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2. The immunogen is located within the last 50 amino acids of CCL2. Amino Acid Squence: ADPKQKWVQDSMDHLD
Predicted Species
Guinea Pig (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCL2
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Pig (81%), Horse (81%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CCL2/MCP1 Antibody [DyLight 488]

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

Monocyte Chemoattracctant Protein-1 (MCP1), also known as CCL2, is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli and is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. MCP1 augments monocyte anti-tumor activity and has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. In atherosclerosis MCP-1 has been implicated to be involved in the recruitment of monocytes into the arterial wall during the disease process.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.
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Bioinformatics

Gene Symbol CCL2