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Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free

Images

 
Immunohistochemistry-Paraffin: Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free [NBP2-79889] - Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin K Antibody (CTSK/2791).
Immunohistochemistry-Paraffin: Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free [NBP2-79889] - Formalin-fixed, paraffin-embedded human Liver Carcinoma stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2791).
Immunohistochemistry-Paraffin: Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free [NBP2-79889] - Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin K Antibody (CTSK/2791).
Protein Array: Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free [NBP2-79889] - Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
CTSK/2791
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

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Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free Summary

Description
1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-79754).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary) (Uniprot: P43235)
Localization
Cytoplasmic
Marker
Marker of Tumor Invasiveness
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CTSK
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1-2 ug/ml
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Protein Array
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Theoretical MW
39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
10 mM PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Cathepsin K Antibody (CTSK/2791) - Azide and BSA Free

  • cathepsin K (pycnodysostosis)
  • Cathepsin K
  • Cathepsin O
  • cathepsin O1
  • Cathepsin O2
  • Cathepsin X
  • CTS02
  • CTSK
  • CTSO
  • CTSO1
  • CTSO2
  • EC 3.4.22
  • EC 3.4.22.38
  • MGC23107
  • PKND
  • PYCD

Background

Cathepsin K is encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CTSK