Cathepsin K Products

Description

Cathepsin K is encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Bioinformatics

Entrez	13038 Mouse 1513 Human 29175 Rat
Uniprot	AAH16058 Human NM_000396 Human NP_000387 Human NP_000387.1 Human O35186 Rat
Product By Gene ID	1513
Alternate Names	cathepsin K (pycnodysostosis) cathepsin K Cathepsin O cathepsin O1 Cathepsin O2 Cathepsin X CTS02 CTSO CTSO1 CTSO2 EC 3.4.22 EC 3.4.22.38 MGC23107 PKND PYCD

Research Areas for Cathepsin K

Find related products by research area and learn more about each of the different research areas below.

Cancer