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Caspr2 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Caspr2 Antibody [NBP1-31358] - Sample: DIV14 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min. Green: Caspr2 protein stained by Caspr2 antibody ...read more
Immunohistochemistry-Frozen: Caspr2 Antibody [NBP1-31358] - Frozen sectioned E13.5 Rat brain. Green: Caspr2 protein stained by Caspr2 antibody [N2N3] diluted at 1:250. Red: beta Tubulin 3/ TUJ1, a mature neuron marker, ...read more
Western Blot: Caspr2 Antibody [NBP1-31358] - Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE; antibody diluted at 1:10000.
Immunohistochemistry-Frozen: Caspr2 Antibody [NBP1-31358] - Caspr2 antibody [N2N3] detects Caspr2n proteins in embryonic mouse brain by immunohistochemical analysis. Sample: Frozen section of embryonic mouse brain ...read more
Western Blot: Caspr2 Antibody [NBP1-31358] - Caspr2 antibody detects Caspr2 protein by Western blot analysis. Whole cell extracts (30 ug) was separated by 5 % SDS-PAGE, and blotted with Caspr2 antibody (NBP1-31358) ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Caspr2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Caspr2. The exact sequence is proprietary.
Localization
Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CNTNAP2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Frozen 1:100-1:1000
  • Western Blot 1:5000-1:20000
Theoretical MW
148 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for Caspr2 Antibody

  • AUTS15
  • Caspr2
  • CASPR2DKFZp781D1846
  • CDFE
  • Cell recognition molecule Caspr2
  • CNTNAP2
  • contactin associated protein-like 2
  • contactin-associated protein 2
  • contactin-associated protein-like 2
  • homolog of Drosophila neurexin IV
  • KIAA0868
  • NRXN4
  • NRXN4Caspr2
  • PTHSL1

Background

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Caspr2 Antibody (NBP1-31358) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CNTNAP2