Caspr2 Antibody (SR1224)

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Western Blot: Caspr2 Antibody (SR1224) [NBP3-22366] - Western blot analysis using NBP3-22366 in Mouse brain lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
SR1224
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Caspr2 Antibody (SR1224) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Caspr2 (Uniprot #: Q9UHC6)
Specificity
Detects endogenous levels of total Caspr2
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CNTNAP2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:500
  • Western Blot 1:500-1:1000
Theoretical MW
160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Caspr2 Antibody (SR1224)

  • AUTS15
  • Caspr2
  • CASPR2DKFZp781D1846
  • CDFE
  • Cell recognition molecule Caspr2
  • CNTNAP2
  • contactin associated protein-like 2
  • contactin-associated protein 2
  • contactin-associated protein-like 2
  • homolog of Drosophila neurexin IV
  • KIAA0868
  • NRXN4
  • NRXN4Caspr2
  • PTHSL1

Background

Caspr2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CNTNAP2