Carboxylesterase 2/CES2 Antibody (4F12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using H00008824-M02	Applications	Species
Uchida K, Otake K, Tanaka K et al. Clinical implications of CES2 RNA expression in neuroblastoma. J Pediatr Surg. 2013-03-01 [PMID: 23480903]
Pratt SE, Durland-Busbice S, Shepard RL et al. Human Carboxylesterase-2 Hydrolyzes the Prodrug of Gemcitabine (LY2334737) and Confers Prodrug Sensitivity to Cancer Cells. Clin Cancer Res 2013-03-01 [PMID: 23325581] (WB, Human)	WB	Human

Array H00008824-M02

• Carboxylesterase 2/CES2 Antibodies
• Carboxylesterase 2/CES2 Lysate
• Carboxylesterase 2/CES2 Protein
• Carboxylesterase 2/CES2 Proteins and Enzymes