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Cannabinoid R2/CB2/CNR2 Antibody (352110R) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with either (A) human Cannabinoid R2/CB2/CNR2 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Cannabinoid R2/CB2/CNR2 Monoclonal Antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
352110R
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Cannabinoid R2/CB2/CNR2 Antibody (352110R) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human embryonic kidney cell line HEK293-derived transfected with human Cannabinoid R2/CB2/CNR2
Met1-Cys360
Accession # NP_001832
Specificity
Detects human Cannabinoid R2/CB2/CNR2 in HEK293 human cell line transfected with human Cannabinoid R2/CB2/CNR2 and not Cannabinoid R1/CB1/CNR1 transfectants in flow cytometry.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cannabinoid R2/CB2/CNR2 Antibody (352110R) [Unconjugated]

  • Cannabinoid R2
  • cannabinoid receptor 2 (macrophage)
  • CannabinoidR2
  • CB-2
  • CB2cannabinoid receptor 2
  • CB2R
  • CNR2
  • CX5
  • CX5testis-dominant CNR2 isoform CB2
  • hCB2

Background

Cannabinoid R2 (Cannabinoid Receptor 2), also called CB2 or CNR2, is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. Cannabinoid R2 is expressed in the periphery, notably by hematopoietic cells, in contrast to Cannabinoid R1 which is expressed predominantly in the central nervous system and gut. Cannabinoid R2 on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C‑terminal tails, human Cannabinoid R2 shares 82% amino acid sequence identity with mouse and rat Cannabinoid R2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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