Canine IFN-gamma Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.

We have publications tested in 1 confirmed species: Canine.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using CAIF00	Applications	Species
S Kim, YS Hyun, HT Park, MK Shin, HS Yoo Mycobacterium intracellulare induces a Th17 immune response via M1-like macrophage polarization in canine peripheral blood mononuclear cells Scientific Reports, 2022-07-12;12(1):11818. 2022-07-12 [PMID: 35821058] (Canine)		Canine
JW Choi, SS Withers, H Chang, JA Spanier, VL De La Trin, H Panesar, BT Fife, R Sciammas, EE Sparger, PF Moore, MS Kent, RB Rebhun, SJ McSorley Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function PLoS ONE, 2020-07-02;15(7):e0235518. 2020-07-02 [PMID: 32614928] (Canine)		Canine
LG Ferreira, M Endrighi, KG Lisenko, MRD de Oliveir, MR Damasceno, JA Claudino, PG Gutierres, AP Peconick, FMOB Saad, MG Zangeronim Oat beta-glucan as a dietary supplement for dogs PLoS ONE, 2018-07-31;13(7):e0201133. 2018-07-31 [PMID: 30063762] (Canine)		Canine
Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis BMC Vet Res, 2016-08-23;12(1):174. 2016-08-23 [PMID: 27553600] (Canine)		Canine
Paoloni M, Mazcko C, Selting K, Lana S, Barber L, Phillips J, Skorupski K, Vail D, Wilson H, Biller B, Avery A, Kiupel M, LeBlanc A, Bernhardt A, Brunkhorst B, Tighe R, Khanna C Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma. PLoS ONE, 2015-06-19;10(6):e0129954. 2015-06-19 [PMID: 26091536] (Canine)		Canine
Ferreira J, Silva L, Longo-Maugeri I, Katz S, Barbieri C Use of a recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi for the Immunotherapy of canine visceral Leishmaniasis. PLoS Negl Trop Dis, 2014-03-13;8(3):e2729. 2014-03-13 [PMID: 24625516] (Canine)		Canine
Goulart MR, Pluhar GE, Ohlfest JR Identification of myeloid derived suppressor cells in dogs with naturally occurring cancer. PLoS ONE, 2012-03-13;7(3):e33274. 2012-03-13 [PMID: 22428007] (Canine)		Canine
Xiong W, Candolfi M, Liu C Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial. PLoS ONE, 2010-06-11;5(6):e11074. 2010-06-11 [PMID: 20552015] (Canine)		Canine
Yuasa K, Yoshimura M, Urasawa N, Ohshima S, Howell JM, Nakamura A, Hijikata T, Miyagoe-Suzuki Y, Takeda S Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products. Gene Ther., 2007-06-21;14(17):1249-60. 2007-06-21 [PMID: 17581597] (Canine)		Canine
Fukumoto S, Tamaki Y, Okamura M, Bannai H, Yokoyama N, Suzuki T, Igarashi I, Suzuki H, Xuan X Prime-boost immunization with DNA followed by a recombinant vaccinia virus expressing P50 induced protective immunity against Babesia gibsoni infection in dogs. Vaccine, 2006-10-10;25(7):1334-41. 2006-10-10 [PMID: 17055131] (Canine)		Canine
Lin TY, London CA A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet. Immunol. Immunopathol., 2006-10-06;114(3):320-34. 2006-10-06 [PMID: 17027994] (Canine)		Canine
Sugiura K, Nishikawa M, Ishiguro K, Tajima T, Inaba M, Torii R, Hatoya S, Wijewardana V, Kumagai D, Tamada H, Sawada T, Ikehara S, Inaba T Effect of ovarian hormones on periodical changes in immune resistance associated with estrous cycle in the beagle bitch. Immunobiology, 2004-01-01;209(8):619-27. 2004-01-01 [PMID: 15638130] (Canine)		Canine
Show All 12 Publications. Collapse Publications.

Array CAIF00

• IFN-gamma Antibodies
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• IFN-gamma Proteins
• IFN-gamma ELISAs
• IFN-gamma Proteins and Enzymes