BNIP3 Antibody - BSA Free

BCL2/adenovirus E1B 19kD protein-interacting protein 3 (BNIP3) is a mitochondrial protein critical for apoptotic events in response to adenovirus infection. It has been implicated in causing a necrotic-like cell death pattern in cells, induced by CD47. This effect has been seen in many cancer cells, and its mis-regulation causes tumor cells to be impervious to normal autophagic events. The tumor suppressor p53 represses the expression of BNIP3, often as a consequence of hypoxic micro-environments as seen in tumors. When BNIP3 is correctly expressed and activated, it translocates to the mitochondria and instigates apoptosis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IHC-P, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-77683	Applications	Species
Heng JS, Rattner A, Stein-O'Brien GL et al. Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. Proc Natl Acad Sci U S A. 2019-04-30 [PMID: 30988181] (ICC/IF, Mouse)	ICC/IF	Mouse
Yang YS, Yang MC, Guo Y et al. PLAGL2 expression-induced lung epithelium damages at bronchiolar alveolar duct junction in emphysema: bNip3- and SP-C-associated cell death/injury activity. Am J Physiol Lung Cell Mol Physiol. 2009-09-01 [PMID: 19574421] (IHC-P, WB, Human, Mouse)	IHC-P, WB	Human, Mouse

Array NBP1-77683

• BNIP3 Antibodies
• BNIP3 Lysate
• BNIP3 Proteins