Orthogonal Strategies: Immunohistochemistry-Paraffin: beta 2-Microglobulin Antibody [NBP1-87482] - Staining in human lymph node and skeletal muscle tissues using anti-B2M antibody. Corresponding B2M RNA-seq data ...read more
Orthogonal Strategies: Western Blot: beta 2-Microglobulin Antibody [NBP1-87482] - Analysis in human cell lines HeLa and HEK293. Corresponding RNA-seq data are presented for the same cell lines. Loading control: ...read more
Immunocytochemistry/ Immunofluorescence: beta 2-Microglobulin Antibody [NBP1-87482] - Staining of human cell line U-251 MG shows localization to plasma membrane, cytosol and the Golgi apparatus. Antibody staining is ...read more
Immunohistochemistry-Paraffin: beta 2-Microglobulin Antibody [NBP1-87482] - Staining of human lymph node shows strong cytoplasmic positivity in germinal center cells.
Immunohistochemistry-Paraffin: beta 2-Microglobulin Antibody [NBP1-87482] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: beta 2-Microglobulin Antibody [NBP1-87482] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons as expected.
Immunohistochemistry-Paraffin: beta 2-Microglobulin Antibody [NBP1-87482] - Staining of human kidney shows moderate cytoplasmic positivity in cells in glomeruli.
This antibody was developed against Recombinant Protein corresponding to amino acids: QRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
B2M
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for beta 2-Microglobulin Antibody
B2M
beta 2Microglobulin
beta 2-Microglobulin
beta chain of MHC class I molecules
beta-2-microglobin
beta-2-microglobulin
Background
Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells (Gussow et al., 1987 [PubMed 3312414]).[supplied by OMIM]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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