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ARHGAP20 Antibody

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Immunohistochemistry-Paraffin: ARHGAP20 Antibody [NBP1-81411] - Staining of human cerebral cortex shows granular cytoplasmic positivity in neuronal cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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ARHGAP20 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KGPRTHRRCSEPNIEDQNRKLTYLRGIYSKKQHKTSCEAGLLHGEEDYLKRHKSLQMEGQKLINQSLVMGIEVGKSSATNQNTE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARHGAP20
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
ARHGAP20 Protein (NBP1-81411PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (86%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ARHGAP20 Antibody

  • KIAA1391Rho-type GTPase-activating protein 20
  • RA and RhoGAP domain containing protein
  • RARHOGAP
  • Rho GTPase activating protein 20
  • rho GTPase-activating protein 20

Background

The ARHGAP20 gene encodes for a Rho GTPase-activating protein 20 that does so by converting them to an inactive GDP-bound state. It exists in four isoforms: 1ad is 1,191 amino acids long at 132 kDA, 1be is 1,165 amino acids long at 130 kDA, 1c is 1,168 amino acids long at 130 kDA, and 1e(1d) is 1,155 amino acids long at nearly 129 kDA. ARHGAP20 participates is signal transduction and Rho GTPase cycle and interacts with various genes such as RHOA, GRB2, SIRT5, TERF2, and BMPR1B. ARHGAP20 has been researched in lymphocytic leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ARHGAP20
Entrez
Uniprot