Recombinant Human Apolipoprotein A-I/ApoA1 Protein

This lyophilized preparation is stable for 12 months from date of receipt at -20 to -70 degrees C, preferably desiccated. Upon reconstitution, the preparation can be stored for 1 month at 2-8 degrees C under sterile conditions, and for 3 months at -20 degrees C to -70 degrees C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Stock solutions should be aliquoted and stored at < -20 degrees C. Further dilutions should be made in appropriate buffered solutions

Apolipoprotein A-I encoded by the APOA1 gene is the major protein component of high density lipoprotein (HDL) in plasma. It has a specific role in lipid metabolism. Apolipoprotein A-I participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). Apolipoprotein A-I is also isolated as a prostacyclin (PGI2) stabilizing factor and thus may have an anticlotting effect. Apolipoprotein A-I has been shown to interact with ABCA1, GPLD1 and PLTP. Apolipoprotein A-I binds to lipopolysaccharide or endotoxin and has a major role in the anti-endotoxin function of HDL. Mature human ApoA-1 shares 65 % and 62 % a.a. sequence identity with murine and rat ApoA-1, respectively. It has an approximate molecular weight of 28.1 kDa.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Array NBP2-34869

• Apolipoprotein A-I/ApoA1 Antibodies
• Apolipoprotein A-I/ApoA1 Antibody Pair
• Apolipoprotein A-I/ApoA1 ELISA Kits
• Apolipoprotein A-I/ApoA1 Lysate
• Apolipoprotein A-I/ApoA1 Proteins
• Apolipoprotein A-I/ApoA1 Proteins and Enzyme
• Apolipoprotein A-I/ApoA1 ELISAs