Angiostatin Antibody (79735) [Unconjugated] - Kringle 1-3

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Plasminogen is the precursor of plasmin, an active serine protease that dissolves the fibrin of blood clots and acts in many other processes such as embryonic development, tissue remodeling, inflammation and tumor invasion. Synthesized in the kidney, plasminogen is found in plasma and many extracellular fluids. Activated by u- or t-plasminogen activator, the single-chain plasminogen is converted to plasmin that consists of a disulfide bond-linked heavy chain A and light chain B. Heavy chain A contains 5 kringle domains and light chain B corresponds to the serine protease domain. A fragment consisting of the first 4 kringle domains has been named angiostatin, a novel angiogenesis inhibitor.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ELISA Development.

Showing Publications 1 - 2 of 2.

Publications using MAB926	Applications	Species
MARWAN EMARA, JOAN ALLALUNIS-TURNER Effect of hypoxia on angiogenesis related factors in glioblastoma cells Oncology Reports 4/1/2014 [PMID: 24573635]
Ponnazhagan S, Mahendra G, Kumar S, Shaw DR, Stockard CR, Grizzle WE, Meleth S Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor. Cancer Res., 2004-03-01;64(5):1781-7. 2004-03-01 [PMID: 14996740] (ELISA Development, Mouse)	ELISA Development	Mouse

Array MAB926

• Angiostatin Antibodies
• Angiostatin ELISA Kit
• Angiostatin Protein
• Angiostatin Proteins and Enzyme