AKR1C2 Antibody (3C11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using H00001646-M03	Applications	Species
Gagliardi M, Cotella D, Santoro C et al. Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis Cell Death Dis 2019-11-28 [PMID: 31780644] (WB, Human)	WB	Human
Hevir N, Vouk K, Sinkovec J et al. Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. Chem Biol Interact. 2011-01-11 [PMID: 21232532]
Takahashi RH, Bains OS, Pfeifer TA et al. Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. Drug Metab Dispos. 2008-03-05 [PMID: 18322072]

Array H00001646-M03

• AKR1C2 Antibodies
• AKR1C2 ELISA Kits
• AKR1C2 Lysates
• AKR1C2 Proteins