Biological Strategies: Western Blot: AGTR-1 Antibody [NBP1-77078] - Effects of Ang(1-7) and/or A-779 treatments to the sham and OVX animals for 6 weeks on the expressions of RAS different proteins and ...read more
Western Blot: AGTR-1 Antibody [NBP1-77078] - Mouse kidney tissue lysate with Angiotensin II Type 1 Receptor antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry: AGTR-1 Antibody - BSA Free [NBP1-77078] - Immunohistochemistry of AGTR-1 in mouse kidney tissue with AGTR-1 antibody at 2.5 ug/ml.
Immunocytochemistry/ Immunofluorescence: AGTR-1 Antibody - BSA Free [NBP1-77078] - Immunofluorescence of AGTR-1 in Mouse Kidney cells with AGTR-1 antibody at 5 ug/mL.
Immunohistochemistry: AGTR-1 Antibody - BSA Free [NBP1-77078] - Immunohistochemistry of AGTR-1 in mouse kidney tissue with AGTR-1 antibody at 2.5 ug/mL.
Antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1. Amino Acid Squence: KKAYEIQKNKPRNDDI
41 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Use in Rabbit reported in scientific literature (PMID:35372645).Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (81%).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified
Alternate Names for AGTR-1 Antibody - BSA Free
AG2S
AGTR1
AGTR-1
AGTR1AAngiotensin II type-1 receptor
Angiostensin Receptor
angiotensin II receptor, type 1
angiotensin receptor 1
angiotensin receptor 1B
AT1
AT1AR
AT1AT1AR
AT1B
AT1BR
AT1R
AT2R1
AT2R1A
AT2R1AGTR1B
AT2R1BAT1BR
HAT1R
type-1 angiotensin II receptor
type-1B angiotensin II receptor
Background
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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