Western Blot: AKAP1 Antibody [NBP1-89172] - Analysis in control (vector only transfected HEK293T lysate) and AKAP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: AKAP1 Antibody [NBP1-89172] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: AKAP1 Antibody [NBP1-89172] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: AKAP1 Antibody [NBP1-89172] - Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: AKAP1 Antibody [NBP1-89172] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: AKAP1 Antibody [NBP1-89172] - Staining of human testis shows strong cytoplasmic positivity in spermatids.
This antibody was developed against Recombinant Protein corresponding to amino acids: EHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSRFIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEATEQV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AKAP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Human reactivity reported in scientific literature (PMID: 23172368).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for AKAP1 Antibody
A kinase (PRKA) anchor protein 1
a kinase anchor protein 1, mitochondrial
AKAP121
AKAP149AKAP 149
AKAP84
A-kinase anchor protein 1, mitochondrial
A-kinase anchor protein 149 kDa
A-kinase anchor protein, 149kD
D-AKAP1
D-AKAP-1
Dual specificity A-kinase-anchoring protein 1
dual-specificity A-kinase anchoring protein 1
MGC1807
PRKA1
protein kinase A anchoring protein 1
protein kinase A1
Protein kinase A-anchoring protein 1
protein kinase anchoring protein 1
S-AKAP84
SAKAP84AKAP
Spermatid A-kinase anchor protein 84
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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