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AGTR-2 Antibody (364805) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
364805
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3659U-100UG
Alexa Fluor 405
FAB3659V-100UG
Alexa Fluor 488
FAB3659G-100UG
Alexa Fluor 532
FAB3659X
Alexa Fluor 594
FAB3659T-100UG
Alexa Fluor 647
FAB3659R-100UG
Alexa Fluor 700
FAB3659N-100UG
Alexa Fluor 750
FAB3659S-100UG
Allophycocyanin
FAB3659A
Allophycocyanin/Cy7
FAB3659APCCY7
Biotin
FAB3659B
DyLight 350
FAB3659D
DyLight 405
FAB3659E
DyLight 488
FAB3659K
DyLight 550
FAB3659L
DyLight 594
FAB3659M
DyLight 650
FAB3659W
DyLight 680
FAB3659Y
DyLight 755
FAB3659Z
FITC
FAB3659F
HRP
FAB3659H
Janelia Fluor 525
FAB3659JF525
Janelia Fluor 549
FAB3659I
Janelia Fluor 646
FAB3659J
Janelia Fluor 669
FAB3659JF669
PE/Atto594
FAB3659PEATT594
PE/Cy5.5
FAB3659PECY55
PE/Cy7
FAB3659PECY7
PerCP
FAB3659C
Phycoerythrin
FAB3659P
Unconjugated
MAB3659
mFluor Violet 450 SE
FAB3659MFV450
mFluor Violet 500 SE
FAB3659MFV500
mFluor Violet 610 SE
FAB3659MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3659
Carrier Free
FAB3659P
Carrier Free
MAB3659
Carrier Free
FAB3659A
Carrier Free
MAB3659-SP
Carrier Free
FAB3659V-100UG
Carrier Free
FAB3659U-100UG
Carrier Free
FAB3659T-100UG
Carrier Free
FAB3659S-100UG
Carrier Free
FAB3659R-100UG
Carrier Free
FAB3659N-100UG
Carrier Free
FAB3659G-100UG
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AGTR-2 Antibody (364805) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
HEK293 human embryonic kidney cell line transfected with human AGTR-2
Met1-Ser363
Accession # P50052
Specificity
Detects human AGTR‑2. Stains human AGTR-2-transfected cells but not irrelevant transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
AGTR2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for AGTR-2 Antibody (364805) [CoraFluor™ 1]

  • AGTR2
  • AGTR-2
  • Angiostensin Receptor
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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AGTR-2 Antibody
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FAB3659CL1
AGTR-2 Antibody (364805) [CoraFluor™ 1]
Species: Hu
Applications: Flow, CyTOF-ready

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Bioinformatics

Gene Symbol AGTR2