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AGTR-2 Antibody (364805) [Allophycocyanin]

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NS0 mouse myeloma cell line was stained with Mouse Anti-Human AGTR-2 APC-conjugated Monoclonal Antibody (Catalog # FAB3659A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
364805
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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AGTR-2 Antibody (364805) [Allophycocyanin] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human AGTR-2
Met1-Ser363
Accession # P50052
Specificity
Detects human AGTR‑2. Stains human AGTR-2-transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
AGTR2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB3659A in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AGTR-2 Antibody (364805) [Allophycocyanin]

  • AGTR2
  • AGTR-2
  • Angiostensin Receptor
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR‑1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR‑1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AGTR-2 Antibody (FAB3659A)(2)

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Bioinformatics

Gene Symbol AGTR2
Uniprot