NS0 mouse myeloma cell line was stained with Mouse Anti-Human AGTR-2 APC-conjugated Monoclonal Antibody (Catalog # FAB3659A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our ...read more
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for AGTR-2 Antibody (364805) [Allophycocyanin]
AGTR2
AGTR-2
Angiostensin Receptor
angiotensin II receptor, type 2
Angiotensin II type-2 receptor
angiotensin receptor 2
AT2
AT2ATGR2
AT2R
MRX88
MRX88type-2 angiotensin II receptor
Background
AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR‑1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR‑1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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