Species: Hu, Mu, Rt, Rb, Sh
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
186 |
| Alternate Names |
- Angiostensin Receptor
- angiotensin II receptor, type 2
- Angiotensin II type-2 receptor
- angiotensin receptor 2
- AT2ATGR2
- MRX88type-2 angiotensin II receptor
|
Research Areas for AGTR-2
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
