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Acrosin Antibody (ACR-2) [Biotin]

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Product Details

Summary
Reactivity Po, Bv(-), Ca(-), Hu(-)Species Glossary
Applications WB, Flow, ICC/IF, CyTOF-ready
Clone
ACR-2
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB500-419AF350
Alexa Fluor 405
NB500-419AF405
Alexa Fluor 488
NB500-419AF488
Alexa Fluor 532
NB500-419AF532
Alexa Fluor 594
NB500-419AF594
Alexa Fluor 647
NB500-419AF647
Alexa Fluor 700
NB500-419AF700
Alexa Fluor 750
NB500-419AF750
Allophycocyanin
NB500-419APC
Allophycocyanin/Cy7
NB500-419APCCY7
CoraFluor 1
NB500-419CL1
DyLight 350
NB500-419UV
DyLight 405
NB500-419V
DyLight 488
NB500-419G
DyLight 550
NB500-419R
DyLight 594
NB500-419DL594
DyLight 650
NB500-419C
DyLight 680
NB500-419FR
DyLight 755
NB500-419IR
FITC
NB500-419F
HRP
NB500-419H
Janelia Fluor 525
NB500-419JF525
Janelia Fluor 549
NB500-419JF549
Janelia Fluor 585
NB500-419JF585
Janelia Fluor 635
NB500-419JF635
Janelia Fluor 646
NB500-419JF646
Janelia Fluor 669
NB500-419JF669
PE
NB500-419PE
PE/Atto594
NB500-419PEATT594
PE/Cy5.5
NB500-419PECY55
PE/Cy7
NB500-419PECY7
Unconjugated
NB500-419
mFluor Violet 450 SE
NB500-419MFV450
mFluor Violet 500 SE
NB500-419MFV500
mFluor Violet 610 SE
NB500-419MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB500-419
BSA Free
NB500-419
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Acrosin Antibody (ACR-2) [Biotin] Summary

Immunogen
Acid extracts of boar spermatozoa were subjected to hydrophobic chromatography and the pooled fraction with reactivity to N-alpha benzoylarginine-4-nitroanilide was used for immunization.
Specificity
The antibody ACR-2 reacts with various forms of porcine acrosin (55, 53, 45 and 35 kDa), a typical serine proteinase with trypsin-like specificity. Acrosin is stored in the acrosome of undamaged spermatozoa.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ACR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Acrosin Antibody (ACR-2) [Biotin]

  • acrosin
  • ACRS
  • preproacrosin
  • proacrosin

Background

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Acrosin Antibody
(ACR-2) [Biotin]
NB500-419B
Acrosin Antibody (ACR-2) [Biotin]
Species: Po, Bv(-), Ca(-), Hu(-)
Applications: WB, Flow, ICC/IF, CyTOF-ready

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Bioinformatics

Gene Symbol ACR