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ACE/CD143 Antibody (JM59-32)

Images

 
Western Blot: ACE/CD143 Antibody (JM59-32) [NBP2-67111] - Analysis of ACE on human lung (1) and mouse kidney (2) tissue lysate using anti-ACE antibody at 1/1,000 dilution.
Immunohistochemistry-Paraffin: ACE/CD143 Antibody (JM59-32) [NBP2-67111] - Analysis of paraffin-embedded mouse testis tissue using anti-ACE antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: ACE/CD143 Antibody (JM59-32) [NBP2-67111] - Analysis of paraffin-embedded human kidney tissue using anti-ACE antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: ACE/CD143 Antibody (JM59-32) [NBP2-67111] - Analysis of paraffin-embedded mouse kidney tissue using anti-ACE antibody. Counter stained with hematoxylin.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, IHC
Clone
JM59-32
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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ACE/CD143 Antibody (JM59-32) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Synthetic peptide within Human ACE/CD143 aa 1,257-1,306 / 1,306. (SwissProt: P12821 Human; SwissProt: P09470 Mouse)
Localization
Secreted. Cell membrane. Cytoplasm.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ACE
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:100
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Western Blot 1:500-1:2000
Publications
Read Publication using
NBP2-67111 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS (pH7.4), 0.05% BSA, 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for ACE/CD143 Antibody (JM59-32)

  • ACE
  • ACE1angiotensin converting enzyme, somatic isoform
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • carboxycathepsin
  • CD143 antigen
  • CD143
  • DCP
  • DCP1
  • DCP1angiotensin-converting enzyme
  • dipeptidyl carboxypeptidase 1
  • Dipeptidyl carboxypeptidase I
  • EC 3.2.1.-
  • EC 3.4.15.1
  • Kininase II
  • MGC26566
  • MVCD3
  • peptidase P
  • testicular ECA

Background

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ACE/CD143 Antibody (NBP2-67111)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


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(1)
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Bioinformatics

Gene Symbol ACE