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ABCA7 Antibody (7A1-144) [DyLight 550]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC
Clone
7A1-144
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 550

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ABCA7 Antibody (7A1-144) [DyLight 550] Summary

Immunogen
Mouse ABCA7 stably-transfected HeLa cells. [UniProt# Q91V24]
Localization
Cell Membrane and Cytoplasmic
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
ABCA7
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ABCA7 Antibody (7A1-144) [DyLight 550]

  • ABCA-SSN
  • ABCXATP-binding cassette sub-family A member 7
  • ATP-binding cassette, sub-family A (ABC1), member 7
  • Autoantigen SS-N
  • EC 2.2.1.1
  • EC 3.6.3
  • EC 3.6.3.41
  • FLJ40025
  • Macrophage ABC transporter

Background

ABCA7, an ATP-binding cassette, sub-family A (ABC1), member 7, is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells and may mediate cholesterol efflux.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ABCA7