Species: Hu
Applications: WB, B/N, ELISA(Cap)
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Mu
Applications: CyTOF-ready, Flow
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
Human
Human
Mouse
Mouse
Human
|
| Product By Gene ID |
246778 |
| Alternate Names |
- IL-27 p28 subunit
- IL-27 subunit alpha
- IL-27
- IL27A
- IL-27-A
- IL27-A
- IL27p28
- IL30
- interleukin 27
- interleukin 30
- interleukin-27 subunit alpha
- MGC71873
- p28IL-27A
|
Research Areas for IL-27
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
![Western Blot IL-27 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IL-27_AF2526_Western_Blot_12085.jpg)
![Neutralization IL-27 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IL-27_AF2526_Block_Neutralize_10278.jpg)
![N/A IL-27 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL27_DY2526_ELISA_2312.jpg)
![Bioactivity IL-27 [Unconjugated]](http://images.novusbio.com/fullsize2/IL-27_2799-ML_676.jpg)
![SDS-PAGE IL-27 [Unconjugated]](http://images.novusbio.com/fullsize2/IL-27_2799-ML_674.jpg)
![Bioactivity IL-27 [Unconjugated]](http://images.novusbio.com/fullsize/11312-il_recombinant-human-il-27-ebi3-p28-heterodimer-protein-cf-bioactivity-2042023113719.jpg)
![SDS-PAGE IL-27 [Unconjugated]](http://images.novusbio.com/fullsize/11312-il_recombinant-human-il-27-ebi3-p28-heterodimer-protein-cf-sds-page-17112022123724.jpg)