Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt, Ze, Po
Applications: WB, ICC/IF, IHC, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP, KO
Host: Rabbit Monoclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
3098 |
| Alternate Names |
- Brain form hexokinase
- EC 2.7.1
- EC 2.7.1.1
- glycolytic enzyme
- hexokinase 1
- Hexokinase type I
- hexokinase-1
- HK I
- HK1-ta
- HK1-tb
- HK1-tc
- HKI
- HXK1
|
Research Areas for Hexokinase 1
Find related products by research area and learn more about each of the different research areas below.
Cancer
