| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-24779SS | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB4227-SP | |||
| Carrier Free | FAB4227S-100UG | |||
| Carrier Free | FAB4227R-100UG | |||
| Carrier Free | FAB4227N-100UG | |||
| Carrier Free | FAB4227V-100UG | |||
| Carrier Free | FAB4227U-100UG | |||
| Carrier Free | FAB4227T-100UG | |||
| Carrier Free | FAB4227G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF4227-SP | |||
| Conjugate | Catalog # | Availability | Size | Price |
|---|---|---|---|---|
| Alexa Fluor 350 | FAB7167U-100UG | |||
| Alexa Fluor 405 | FAB7167V-100UG | |||
| Alexa Fluor 488 | FAB7167G-100UG | |||
| Alexa Fluor 594 | FAB7167T-100UG | |||
| Alexa Fluor 647 | FAB7167R-100UG | |||
| Alexa Fluor 700 | FAB7167N-100UG | |||
| Alexa Fluor 750 | FAB7167S-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB7167-SP | |||
| Carrier Free | FAB7167V-100UG | |||
| Carrier Free | FAB7167U-100UG | |||
| Carrier Free | FAB7167T-100UG | |||
| Carrier Free | FAB7167S-100UG | |||
| Carrier Free | FAB7167R-100UG | |||
| Carrier Free | FAB7167N-100UG | |||
| Carrier Free | FAB7167G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB4227R-SP | |||
| Carrier Free | FAB4227RG-100UG | |||
| Carrier Free | FAB4227RV-100UG | |||
| Carrier Free | FAB4227RU-100UG | |||
| Carrier Free | FAB4227RT-100UG | |||
| Carrier Free | FAB4227RS-100UG | |||
| Carrier Free | FAB4227RR-100UG | |||
| Carrier Free | FAB4227RN-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB42273R-SP | |||
| Carrier Free | FAB42273RV-100UG | |||
| Carrier Free | FAB42273RU-100UG | |||
| Carrier Free | FAB42273RT-100UG | |||
| Carrier Free | FAB42273RS-100UG | |||
| Carrier Free | FAB42273RR-100UG | |||
| Carrier Free | FAB42273RN-100UG | |||
| Carrier Free | FAB42273RG-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB42274-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB8399-SP | |||
| Carrier Free | FAB8399V-100UG | |||
| Carrier Free | FAB8399U-100UG | |||
| Carrier Free | FAB8399T-100UG | |||
| Carrier Free | FAB8399S-100UG | |||
| Carrier Free | FAB8399R-100UG | |||
| Carrier Free | FAB8399N-100UG | |||
| Carrier Free | FAB8399G-100UG | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB8399R-SP | |||
| Carrier Free | FAB8399RR-100UG | |||
| Carrier Free | FAB8399RV-100UG | |||
| Carrier Free | FAB8399RG-100UG | |||
| Carrier Free | FAB8399RT-100UG | |||
| Carrier Free | FAB8399RS-100UG | |||
| Carrier Free | FAB8399RN-100UG | |||
| Carrier Free | FAB8399RU-100UG | |||
![Impact of CXCR7 over-expression on the E2-dependent and -independent growth of MCF-7 cells.MCF-7 cells were transiently transfected with either a control expression vector or one containing the human CXCR7 open reading frame. (A) Total protein extracts were prepared 48 h after transfection, and a Western blot analysis was performed to confirm CXCR7 over-expression. (B) Transfected cells were cultured in the presence of EtOH (−) or 10−8 M E2 (+) for seven days. E2-dependent and E2-independent cell growth rates were then evaluated by cell count of three independent experiments (n = 3). The results are expressed as a percentage of the relative cell number obtained from control cells treated with E2 (considered as 100%). Significant differences (p<0.05) between transfected cells in the absence of E2 are indicated by an asterisk and between transfected cells in the presence of E2 by a sharp symbol. (C) A proposed model for the involvement of the CXCL12 signaling axis in E2-dependent and -independent cell growth is shown. The binding of CXCL12 to CXCR4 and CXCR7 leads to the stimulation of cell growth through diverse pathways [28]. CXCR7 can also modulate CXCL12 availability by removing the chemokine from the extracellular space (left panel). Estrogens could stimulate cell growth by favoring the activation of CXCL12 through CXCR4 and reducing the expression of CXCR7 (right panel). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/21695171), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/mab42273_human-cxcr7-rdc-1-mab-clone-11g8-812025557241.jpg)
![Simple Western: CXCR7/RDC-1 Antibody [NBP2-24779] - Lane view shows a specific band for CXCR7 in 0.5 mg/mL of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Simple-Western-NBP2-24779-img0003.jpg "Simple Western: CXCR7/RDC-1 Antibody [NBP2-24779] - Lane view shows a specific band for CXCR7 in 0.5 mg/mL of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.")
![Immunohistochemistry-Paraffin: CXCR7/RDC-1 Antibody [NBP2-24779] - Analysis of a FFPE tissue section of human tonsil using 5 ug/mL concentration of CXCR7/RDC-1 antibody. The staining was developed using HRP labeled anti-rabbit secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin. This CXCR7 antibody generated a specific membrane cytoplasmic staining in most of the cells, and the signal was highest/very intense in the endothelial cells/blood vessels.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunohistochemistry-Paraffin-NBP2-24779-img0006.jpg)
![Immunohistochemistry-Paraffin: CXCR7/RDC-1 Antibody [NBP2-24779] - Analysis of a FFPE tissue section of human tonsil using 5 ug/mL concentration of CXCR7/RDC-1 antibody. The staining was developed using HRP labeled anti-rabbit secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin. This CXCR7 antibody generated a specific membrane cytoplasmic staining in most of the cells, and the signal was highest/very intense in the endothelial cells/blood vessels.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunohistochemistry-Paraffin-NBP2-24779-img0007.jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP2-24779] - Total protein from human spleen, tonsil, lymph node and mouse spleen was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/mL anti-CXCR7 in 1% BSA in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Western-Blot-NBP2-24779-img0008.jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Western-Blot-NBP1-31309-img0012.jpg "Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.")
![Immunocytochemistry/Immunofluorescence: CXCR7/RDC-1 Antibody [NBP1-31309] - Analysis of human pancreatic cancer cell line, using CCR7 antibody at 1:50 dilution. Blue: DAPI.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-31309-img0007.jpg)
![Immunohistochemistry-Paraffin: CXCR7/RDC-1 Antibody [NBP1-31309] - Human gastric cancer, using CXCR7 antibody at 1:100 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunohistochemistry-Paraffin-NBP1-31309-img0010.jpg)
![Immunohistochemistry: CXCR7/RDC-1 Antibody [NBP1-31309] - Human pancreatic tumor, using CXCR7 antibody at 1:100 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunohistochemistry-NBP1-31309-img0008.jpg)
![Immunohistochemistry: CXCR7/RDC-1 Antibody [NBP1-31309] - Human pancreatic tumor, using CXCR7 antibody at 1:100 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunohistochemistry-NBP1-31309-img0009.jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] - Unboiled Raji whole cell and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.](http://images.novusbio.com/fullsize/antibody/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-western-blot-12120249813..jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] -Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301)) was used to detect the primary antibody.](http://images.novusbio.com/fullsize/antibody/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-western-blot-12120249944..jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] -Rat tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.](http://images.novusbio.com/fullsize/antibody/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-western-blot-12120249115..jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] -Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.](http://images.novusbio.com/fullsize/antibody/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-western-blot-121202491219..jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] -Boiled and unboiled Raji whole cell and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7 antibody [C1C2], Internal diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. (WCE: whole cell extract; ME: membrane extract)](http://images.novusbio.com/fullsize/antibody/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-western-blot-121202491348..jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP1-31309] - Unboiled Raji whole cell and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR7/RDC-1 antibody [C1C2], Internal (NBP1-31309) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)](http://images.novusbio.com/fullsize/nbp1-31309_rabbit-polyclonal-cxcr7-rdc-1-antibody-9102024205633.jpg)
![Western Blot: CXCR7/RDC-1 Antibody [NBP2-58162] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Western-Blot-NBP2-58162-img0002.jpg "Western Blot: CXCR7/RDC-1 Antibody [NBP2-58162] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.")
![Immunocytochemistry/Immunofluorescence: CXCR7/RDC-1 Antibody [NBP2-58162] - Staining of human cell line U-2 OS shows localization to plasma membrane & vesicles. Antibody staining is shown in green.](http://images.novusbio.com/fullsize/CXCR7-RDC-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58162-img0001.jpg)
