NFATC2/NFAT1 Products

Description

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1, NFAT2, NFAT3, and NFAT4. These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.

Bioinformatics

Uniprot	NP_036472 Human NP_036472.2 Human NP_775114 Human NP_775114.1 Human Q13469 Human
Product By Gene ID	4773
Alternate Names	NFAT pre-existing subunit NFAT transcription complex, preexisting component NFAT1nuclear factor of activated T-cells, cytoplasmic 2 NFATc2 NF-ATc2 NFATp NF-ATP NF-ATp NFATPnuclear factor of activated T-cells, preexisting component nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 preexisting nuclear factor of activated T-cells 2 T cell transcription factor NFAT1 T-cell transcription factor NFAT1

Research Areas for NFATC2/NFAT1

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology
Phospho-Specific
Transcription Factors and Regulators
Wnt Signaling Pathway