Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ch, RM
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
51510 |
| Alternate Names |
- apoptosis-related protein PNAS-2
- C9orf83
- charged multivesicular body protein 5
- chromatin modifying protein 5
- Chromatin-modifying protein 5
- chromosome 9 open reading frame 83
- HSPC177
- hVps60
- PNAS-2
- SNF7 domain containing 2
- SNF7 domain-containing protein 2
- SNF7DC2
- Vacuolar protein sorting-associated protein 60
- Vps60CGI-34
|
