Species: Hu, Pm
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
ATP-binding cassette sub-family E member 1 (ABCE1) is a member of the ATP-binding cassette sub-family E, but is not a membrane transporter.
ABCE-1 interacts with RNASEL to inhibit its endoribonuclease activity, and antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. ABCE1 is activated by encephalomyocarditis virus (EMCV) and HIV-1, and recently it has been found to be essential for the assembly of immature immunodeficiency virus capsids.
ABCE1 antibodies are useful tools for HIV studies and research on the ATP-binding cassette families.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
6059 |
Alternate Names |
- 2'-5'-oligoadenylate-binding protein
- ATP-binding cassette, sub-family E (OABP), member 1
- HuHP68
- huHP68
- OABP
- Ribonuclease 4 inhibitor
- ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor
- RLIABC38
- RNase L inhibitor
- RNASEL1
- RNASELIRNS4IATP-binding cassette sub-family E member 1
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