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ABCE1 Antibody [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB400-116AF350
Alexa Fluor 405
NB400-116AF405
Alexa Fluor 488
NB400-116AF488
Alexa Fluor 532
NB400-116AF532
Alexa Fluor 594
NB400-116AF594
Alexa Fluor 647
NB400-116AF647
Alexa Fluor 700
NB400-116AF700
Alexa Fluor 750
NB400-116AF750
Allophycocyanin
NB400-116APC
Biotin
NB400-116B
CoraFluor 1
NB400-116CL1
DyLight 350
NB400-116UV
DyLight 405
NB400-116V
DyLight 488
NB400-116G
DyLight 550
NB400-116R
DyLight 594
NB400-116DL594
DyLight 650
NB400-116C
DyLight 680
NB400-116FR
DyLight 755
NB400-116IR
FITC
NB400-116F
HRP
NB400-116H
Janelia Fluor 525
NB400-116JF525
Janelia Fluor 669
NB400-116JF669
PE
NB400-116PE
PerCP
NB400-116PCP
Unconjugated
NB400-116
mFluor Violet 450 SE
NB400-116MFV450
mFluor Violet 500 SE
NB400-116MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB400-116
BSA Free
NB400-116
BSA Free
NB400-116SS
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ABCE1 Antibody [mFluor Violet 610 SE] Summary

Immunogen
A fusion protein containing amino acids 1-119 of human ABCE1 [UniProt# P61221]
Localization
Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCE1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Monkey reactivity reported in scientific literature (PMID: 25227463).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ABCE1 Antibody [mFluor Violet 610 SE]

  • 2'-5'-oligoadenylate-binding protein
  • ATP-binding cassette, sub-family E (OABP), member 1
  • huHP68
  • OABP
  • Ribonuclease 4 inhibitor
  • ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor
  • RLIABC38
  • RNase L inhibitor
  • RNASEL1
  • RNASELIRNS4IATP-binding cassette sub-family E member 1

Background

ATP-binding cassette sub-family E member 1 (ABCE1) is a member of the ATP-binding cassette sub-family E, but is not a membrane transporter.

ABCE-1 interacts with RNASEL to inhibit its endoribonuclease activity, and antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. ABCE1 is activated by encephalomyocarditis virus (EMCV) and HIV-1, and recently it has been found to be essential for the assembly of immature immunodeficiency virus capsids.

ABCE1 antibodies are useful tools for HIV studies and research on the ATP-binding cassette families.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ABCE1