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ABCE1 Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB400-116AF350
Alexa Fluor 405
NB400-116AF405
Alexa Fluor 488
NB400-116AF488
Alexa Fluor 532
NB400-116AF532
Alexa Fluor 594
NB400-116AF594
Alexa Fluor 647
NB400-116AF647
Alexa Fluor 700
NB400-116AF700
Alexa Fluor 750
NB400-116AF750
Allophycocyanin
NB400-116APC
Biotin
NB400-116B
CoraFluor 1
NB400-116CL1
DyLight 350
NB400-116UV
DyLight 405
NB400-116V
DyLight 488
NB400-116G
DyLight 550
NB400-116R
DyLight 594
NB400-116DL594
DyLight 650
NB400-116C
DyLight 680
NB400-116FR
DyLight 755
NB400-116IR
FITC
NB400-116F
HRP
NB400-116H
Janelia Fluor 669
NB400-116JF669
PE
NB400-116PE
PerCP
NB400-116PCP
Unconjugated
NB400-116
mFluor Violet 450 SE
NB400-116MFV450
mFluor Violet 500 SE
NB400-116MFV500
mFluor Violet 610 SE
NB400-116MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB400-116
BSA Free
NB400-116
BSA Free
NB400-116SS
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ABCE1 Antibody [Janelia Fluor® 525] Summary

Immunogen
A fusion protein containing amino acids 1-119 of human ABCE1 [UniProt# P61221]
Localization
Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCE1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Monkey reactivity reported in scientific literature (PMID: 25227463).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ABCE1 Antibody [Janelia Fluor® 525]

  • 2'-5'-oligoadenylate-binding protein
  • ATP-binding cassette, sub-family E (OABP), member 1
  • huHP68
  • OABP
  • Ribonuclease 4 inhibitor
  • ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor
  • RLIABC38
  • RNase L inhibitor
  • RNASEL1
  • RNASELIRNS4IATP-binding cassette sub-family E member 1

Background

ATP-binding cassette sub-family E member 1 (ABCE1) is a member of the ATP-binding cassette sub-family E, but is not a membrane transporter.

ABCE-1 interacts with RNASEL to inhibit its endoribonuclease activity, and antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. ABCE1 is activated by encephalomyocarditis virus (EMCV) and HIV-1, and recently it has been found to be essential for the assembly of immature immunodeficiency virus capsids.

ABCE1 antibodies are useful tools for HIV studies and research on the ATP-binding cassette families.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ABCE1