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XRCC1 [p Ser461] Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-533AF350
Alexa Fluor 405
NB100-533AF405
Alexa Fluor 488
NB100-533AF488
Alexa Fluor 532
NB100-533AF532
Alexa Fluor 594
NB100-533AF594
Alexa Fluor 647
NB100-533AF647
Alexa Fluor 700
NB100-533AF700
Alexa Fluor 750
NB100-533AF750
Allophycocyanin
NB100-533APC
Biotin
NB100-533B
CoraFluor 1
NB100-533CL1
DyLight 350
NB100-533UV
DyLight 405
NB100-533V
DyLight 488
NB100-533G
DyLight 550
NB100-533R
DyLight 594
NB100-533DL594
DyLight 650
NB100-533C
DyLight 680
NB100-533FR
DyLight 755
NB100-533IR
FITC
NB100-533F
HRP
NB100-533H
Janelia Fluor 525
NB100-533JF525
Janelia Fluor 549
NB100-533JF549
Janelia Fluor 646
NB100-533JF646
PE
NB100-533PE
PerCP
NB100-533PCP
Unconjugated
NB100-533
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XRCC1 [p Ser461] Antibody [Janelia Fluor® 669] Summary

Immunogen
The immunogen recognized by this antibody maps to a region of surrounding residue Ser 461 of human X-ray Repair Complementing protein 1 using the numbering given in SwissProt entry P18887 (GeneID 7515).
Modification
p Ser461
Specificity
NB100-533 is specific for phospho serine human XRCC1 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
XRCC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for XRCC1 [p Ser461] Antibody [Janelia Fluor® 669]

  • DNA repair protein XRCC1
  • RCC
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • X-ray repair cross-complementing protein 1
  • X-ray-repair, complementing defective, repair in Chinese hamster

Background

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA Ligase III-a.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol XRCC1