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Vitamin D BP Antibody (359501)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
359501
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Vitamin D BP Antibody (359501) Summary

Immunogen
Human plasma-derived Vitamin D BP
Accession # P02774
Specificity
Detects human plasma-derived Vitamin D BP in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
GC
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Reviewed Applications
Read 1 Review rated 5
using
MAB3778 in the following application:

Publications
Read Publication using MAB3778.

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Vitamin D BP Antibody (359501)

  • DBP
  • DBP/GC
  • DBP-MAF
  • DBPVDBG
  • EC 6.3.1.5
  • Gc
  • gc-globulin
  • Gc-MAF
  • GRD3
  • group-specific component (vitamin D binding protein)
  • Group-specific component
  • hDBP
  • VDB
  • VDBG
  • VDBP
  • Vitamin D BP
  • vitamin D-binding alpha-globulin
  • vitamin D-binding protein

Background

Vitamin D BP (VitD BP), also called VDB, DBP, Group Specific Component (Gc) or macrophage-activating factor (DBP- or Gc-MAF), is a member of the albumin family. These plasma/body fluid proteins have a conserved pattern of cysteine motifs that form binding domains. VitD BP is predominantly produced by hepatic parenchymal cells. It transports VitD, activates macrophages and osteoclasts, and enhances C5a chemotactic activity. Over 80 variant alleles have been identified, some of which correlate with osteoporosis or prostate cancer. Human and mouse VitD BP share 78% aa identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vitamin D BP Antibody (MAB3778)(1)

Review for Vitamin D BP Antibody (MAB3778) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using MAB3778:
Filter by Applications
IHC-Fr
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen Vitamin D BP MAB3778
Enlarge
5
reviewed by:
Tatjana Bosnjak
IHC-Fr Mouse 09/09/2019
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedKidney tissue
SpeciesMouse
LotYSD021905A

Comments

CommentsMAB3778 concentration used was 1 µg/ml. Secondary antibody was Alexa Fluor conjugated goat anti-mouse 594 (red; 1:1000).

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Vitamin D BP Antibody (MAB3778) (0)

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Tatjana Bosnjak
09/09/2019
Application: IHC-Fr
Species: Mouse

Bioinformatics

Gene Symbol GC
Uniprot