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ULBP-2 Antibody - Azide and BSA Free

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Western Blot: ULBP-2 Antibody [NBP2-94044] - Western blot analysis of extracts of various cell lines, using ULBP-2 antibody (NBP2-94044) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Western Blot: ULBP-2 Antibody [NBP2-94044] - Western blot analysis of extracts of various cell lines, using ULBP-2 antibody (NBP2-94044) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP2-94044-0.02ml
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ULBP-2 Antibody - Azide and BSA Free Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ULBP-2 (NP_079493.1). EQLRDIQLENYTPKE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ULBP2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:100 - 1:500
Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for ULBP-2 Antibody - Azide and BSA Free

  • ALCAN-alpha
  • N2DL2
  • N2DL-2
  • NKG2D ligand 2
  • NKG2DL2
  • RAET1H
  • RAET1HNKG2DL2
  • retinoic acid early transcript 1 H
  • Retinoic acid early transcript 1H
  • UL16 binding protein 2
  • UL16-binding protein 2
  • ULBP2
  • ULBP-2

Background

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ULBP-2 Antibody -
Azide and BSA Free
NBP2-94044
ULBP-2 Antibody - Azide and BSA Free
Species: Hu
Applications: WB, ELISA

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Bioinformatics

Gene Symbol ULBP2