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TRPM7 Antibody

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Immunohistochemistry-Paraffin: TRPM7 Antibody [NB100-810] - (4ug/ml) staining of paraffin embedded Mouse Hippocampus. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Similar results were obtained after ...read more

Product Details

Summary
Reactivity Mu, Rt, Hu, Po, CaSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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TRPM7 Antibody Summary

Immunogen
Peptide with sequence C-TKESESTNSVRLML, from the C Terminus of the protein sequence according to NP_060142.3; NP_001288141.1.
Predicted Species
Human (100%), Porcine (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TRPM7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 4 - 6 ug/ml
  • Immunohistochemistry-Paraffin 4 - 6 ug/ml
  • Peptide ELISA Detection Limit 1:8000
Application Notes
IHC-P: Mouse brain shows neuronal staining in the hippocampus. IHC successful usage on rat hippocampus is reported in scientific literature (PMID: 19734892). The observed MW corresponds to earlier findings in scientific literature with different antibodies (PMID: 18365021).
Publications
Read Publication using NB100-810.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRPM7 Antibody

  • CHAK
  • CHAK1FLJ25718
  • Channel-kinase 1
  • EC 2.7.11.1
  • Long transient receptor potential channel 7
  • LTRPC ion channel family member 7
  • LTrpC7
  • LTrpC-7
  • LTRPC7FLJ20117
  • transient receptor potential cation channel subfamily M member 7
  • transient receptor potential cation channel, subfamily M, member 7
  • transient receptor potential-phospholipase C-interacting kinase
  • TRP-PLIK

Background

The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase, phosphorylating proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRPM7 Antibody (NB100-810)(1)

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Research Areas for TRPM7 Antibody (NB100-810)

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Blogs on TRPM7.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

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Bioinformatics

Gene Symbol TRPM7
Entrez
Uniprot