Recombinant Human Transgelin/TAGLN/SM22 alpha His Protein

TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publication 1 - 1 of 1.

Publication using NBP1-45267	Applications	Species
Piche J, Gosset N, Legault L et al. Molecular signature of CAID syndrome: non-canonical roles of SGO1 in regulation of TGF-B signalling and epigenomics Sensors and Actuators B: Chemical 2019-01-01 [PMID: 30739867] (IF/IHC, Human)	IF/IHC	Human

Array NBP1-45267

• Transgelin/TAGLN/SM22 alpha Antibodies
• Transgelin/TAGLN/SM22 alpha ELISA Kits
• Transgelin/TAGLN/SM22 alpha Lysates
• Transgelin/TAGLN/SM22 alpha Proteins