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TRAILR3/TNFRSF10C Antibody (TR3.06) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC
Clone
TR3.06
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-80071AF350
Alexa Fluor 405
NBP2-80071AF405
Alexa Fluor 488
NBP2-80071AF488
Alexa Fluor 532
NBP2-80071AF532
Alexa Fluor 594
NBP2-80071AF594
Alexa Fluor 647
NBP2-80071AF647
Alexa Fluor 700
NBP2-80071AF700
Alexa Fluor 750
NBP2-80071AF750
Allophycocyanin
NBP2-80071APC
Biotin
NBP2-80071B
CoraFluor 1
NBP2-80071CL1
DyLight 350
NBP2-80071UV
DyLight 405
NBP2-80071V
DyLight 488
NBP2-80071G
DyLight 550
NBP2-80071R
DyLight 650
NBP2-80071C
DyLight 680
NBP2-80071FR
DyLight 755
NBP2-80071IR
FITC
NBP2-80071F
HRP
NBP2-80071H
Janelia Fluor 525
NBP2-80071JF525
Janelia Fluor 549
NBP2-80071JF549
Janelia Fluor 585
NBP2-80071JF585
Janelia Fluor 635
NBP2-80071JF635
Janelia Fluor 646
NBP2-80071JF646
Janelia Fluor 669
NBP2-80071JF669
PE
NBP2-80071PE
PerCP
NBP2-80071PCP
Unconjugated
NBP2-80071
mFluor Violet 450 SE
NBP2-80071MFV450
mFluor Violet 500 SE
NBP2-80071MFV500
mFluor Violet 610 SE
NBP2-80071MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-80071
BSA Free
NBP2-80071
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TRAILR3/TNFRSF10C Antibody (TR3.06) [DyLight 594] Summary

Immunogen
Recombinant human TRAILR3/TNFRSF10C (DcR1).
Specificity
Recognizes human TRAILR3/TNFRSF10C. Does not cross-react with human TRAIL-R1, -R2 or -R4.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10C
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRAILR3/TNFRSF10C Antibody (TR3.06) [DyLight 594]

  • Antagonist decoy receptor for TRAIL/Apo-2L
  • CD263 antigen
  • CD263
  • cytotoxic TRAIL receptor-3
  • DcR1
  • DCR1MGC149502
  • Decoy receptor 1
  • Decoy TRAIL receptor without death domain
  • LITMGC149501
  • Lymphocyte inhibitor of TRAIL
  • TNFRSF10C
  • TRAIL R3
  • TRAIL receptor 3
  • TRAIL receptor without an intracellular domain
  • TRAILR3
  • TRAIL-R3
  • TRAILR3TNF-related apoptosis-inducing ligand receptor 3
  • TRIDDCR1-TNFR
  • tumor necrosis factor receptor superfamily member 10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Background

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFRSF10C