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TMEM37 Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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TMEM37 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human TMEM37.

Source: E. coli

Amino Acid Sequence: LMVSQLCEDKHSQCKWVMGS

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
TMEM37
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-47602.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for TMEM37 Recombinant Protein Antigen

  • Neuronal voltage-gated calcium channel gamma-like subunit
  • transmembrane protein 37PRPR1
  • voltage-dependent calcium channel gamma subunit-like protein
  • voltage-dependent calcium channel gamma-like subunit

Background

The TMEM37 gene codes for a 190 amino acid long, 20 kDA transmembrane protein that is thought to stabilize the calcium channel in an inactivated state and monitors calcium current when coexpressed with CACNA1G. The TMEM37 gene is associated with food allergies, leukemia, and neuronitis and has been known to interact with genes HBP1, MPP3, ORM1, TNFRSF14, and TNFRSF11A. It plays a role in the MAPK signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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TMEM37 Recombinant
Protein Antigen
NBP2-47602PEP
TMEM37 Recombinant Protein Antigen
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Bioinformatics

Gene Symbol TMEM37