TGF-alpha Antibody

Transforming growth factor alpha (TGFalpha) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFalpha is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFalpha binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor beta. TGFalpha is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFalpha bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using NBP1-87501	Applications	Species
Badawy AA, El-Hindawi A, Hammam O et al. Impact of epidermal growth factor receptor and transforming growth factor-alpha on hepatitis C virus-induced hepatocarcinogenesis. APMIS. 2015-08-17 [PMID: 26279457] (IHC-P, Human) Details: TGF alpha antibody was used for IHC-P on sections from archival liver biopsies of patients with chronic hepatitis C /CHC, hepatocellular carcinoma/HCC as well as normal controls. The antibody was used at a dilution of 1:50 with ultravision HRP Polymer - DAB detection system (Figure 2).	IHC-P	Human

Array NBP1-87501

• TGF-alpha Antibodies
• TGF-alpha ELISA Kit
• TGF-alpha Lysate
• TGF-alpha Proteins
• TGF-alpha Proteins and Enzyme
• TGF-alpha ELISAs