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TFF2 Antibody

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Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Analysis in human stomach and tonsil tissues using NBP2-34032 antibody. Corresponding TFF2 RNA-seq data are presented for the same tissues.
Orthogonal Strategies: Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Analysis in human stomach and tonsil tissues using NBP2-34032 antibody. Corresponding TFF2 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Staining of human Stomach shows strong membranous and cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Staining of human Skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Staining of human Skin shows no positivity in squamous epithelial cells as expected.
Immunohistochemistry-Paraffin: TFF2 Antibody [NBP2-34032] - Staining of human Tonsil shows no positivity in non-germinal center cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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TFF2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: PHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWC
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TFF2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TFF2 Protein (NBP2-34032PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (83%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TFF2 Antibody

  • SML1
  • SML1trefoil factor 2, SML1, human spasmolytic polypeptide (SP)10spasmolytic protein 1
  • SP
  • Spasmolysin
  • Spasmolytic Polypeptide
  • TFF2
  • trefoil factor 2

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TFF2
Uniprot