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TDG Antibody (2F7) - BSA Free

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Western Blot: TDG Antibody (2F7) [NBP2-22589] - The cell lysates of HeLa (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TDG antibody (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Western Blot: TDG Antibody (2F7) [NBP2-22589] - The cell lysates of HeLa (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TDG antibody (1:250). Proteins were visualized using a ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
2F7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-22589AF350
Alexa Fluor 405
NBP2-22589AF405
Alexa Fluor 488
NBP2-22589AF488
Alexa Fluor 532
NBP2-22589AF532
Alexa Fluor 594
NBP2-22589AF594
Alexa Fluor 647
NBP2-22589AF647
Alexa Fluor 700
NBP2-22589AF700
Alexa Fluor 750
NBP2-22589AF750
Biotin
NBP2-22589B
CoraFluor 1
NBP2-22589CL1
DyLight 350
NBP2-22589UV
DyLight 405
NBP2-22589V
DyLight 488
NBP2-22589G
DyLight 550
NBP2-22589R
DyLight 594
NBP2-22589DL594
DyLight 650
NBP2-22589C
DyLight 680
NBP2-22589FR
DyLight 755
NBP2-22589IR
FITC
NBP2-22589F
HRP
NBP2-22589H
Janelia Fluor 525
NBP2-22589JF525
Janelia Fluor 549
NBP2-22589JF549
Janelia Fluor 585
NBP2-22589JF585
Janelia Fluor 635
NBP2-22589JF635
Janelia Fluor 646
NBP2-22589JF646
Janelia Fluor 669
NBP2-22589JF669
mFluor Violet 450 SE
NBP2-22589MFV450
mFluor Violet 500 SE
NBP2-22589MFV500
mFluor Violet 610 SE
NBP2-22589MFV610
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TDG Antibody (2F7) - BSA Free Summary

Immunogen
Recombinant human TDG (1-410aa) purified from E. coli
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TDG
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:250

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for TDG Antibody (2F7) - BSA Free

  • EC 3.2.2.29
  • TDG
  • thymine-DNA glycosylaseG/T mismatch-specific thymine DNA glycosylase

Background

G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence homology with this protein. The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TDG
Uniprot