TAK1 Antibody - BSA Free

TAK1 (TGF-beta activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3. Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation, while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-76441	Applications	Species
Pierre-Marie Boutanquoi, Amira Sayed Khan, Lidia Cabeza, Lucas Jantzen, Thomas Gautier, Semen Yesylevskyy, Christophe Ramseyer, David Masson, Vincent Van Waes, Aziz Hichami, Naim Akhtar Khan A novel fatty acid analogue triggers CD36–GPR120 interaction and exerts anti-inflammatory action in endotoxemia Cellular and Molecular Life Sciences 2024-04-10 [PMID: 38598021]

Array NBP1-76441

• TAK1 Antibodies
• TAK1 Lysate
• TAK1 Proteins